NILE CHEMICALS

N-ACETYL-L-TYROSINE

 

1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

Product identifiers

Product name : N-Acetyl-L-tyrosine

CAS-No. : 537-55-3

 

2. HAZARDS IDENTIFICATION

Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP]

Serious eye damage (Category 1)

Classification according to EU Directives 67/548/EEC or 1999/45/EC

Risk of serious damage to eyes.

Label elements

Labelling according Regulation (EC) No 1272/2008 [CLP]

Pictogram

Signal word Danger

Hazard statement(s)

H318 Causes serious eye damage.

Precautionary statement(s)

P280 Wear protective gloves/ eye protection/ face protection.

P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove

contact lenses, if present and easy to do. Continue rinsing.

Supplemental Hazard

Statements

none

According to European Directive 67/548/EEC as amended.

Hazard symbol(s)

Sigma - T4446 Page 2 of 6

R-phrase(s)

R41 Risk of serious damage to eyes.

S-phrase(s)

S26 In case of contact with eyes, rinse immediately with plenty of water and

seek medical advice.

S39 Wear eye/face protection.

Other hazards - none

 

3. COMPOSITION/INFORMATION ON INGREDIENTS

Substances

Formula : C11H13NO4

Molecular Weight : 223,23 g/mol

Component Concentration

N-Acetyl-L-tyrosine

CAS-No.

EC-No.

537-55-3

208-671-3

 

4. FIRST AID MEASURES

Description of first aid measures

General advice Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact Wash off with soap and plenty of water. Consult a physician.

In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

Indication of immediate medical attention and special treatment needed no data available

 

5. FIRE-FIGHTING MEASURES

Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

Special hazards arising from the substance or mixture

Carbon oxides, nitrogen oxides (NOx)

Nature of decomposition products not known.

Carbon oxides, nitrogen oxides (NOx)

Precautions for fire-fighters

Wear self contained breathing apparatus for fire fighting if necessary.

Further information no data available

 

6. ACCIDENTAL RELEASE MEASURES

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure

adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust.

Environmental precautions Do not let product enter drains.

Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed

containers for disposal.

Reference to other sections For disposal see section 13.

 

7. HANDLING AND STORAGE

Precautions for safe handling

Avoid formation of dust and aerosols.

Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire

protection.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

Specific end uses

no data available

 

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Control parameters

Components with workplace control parameters

Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at

the end of workday.

Personal protective equipment

Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under

appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique

(without touching glove's outer surface) to avoid skin contact with this product. Dispose of

contaminated gloves after use in accordance with applicable laws and good laboratory practices.

Wash and dry hands.

The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the

standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected

according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full-face particle

respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering

controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use

respirators and components tested and approved under appropriate government standards such as

NIOSH (US) or CEN (EU).

Sigma - T4446 Page 4 of 6

 

9. PHYSICAL AND CHEMICAL PROPERTIES

Information on basic physical and chemical properties

a) Appearance Form: solid

Colour: white

b) Odour no data available

c) Odour Threshold no data available

d) pH no data available

e) Melting/freezing point Melting point/range: 149 - 152 °C

f) Initial boiling point and

boiling range

no data available

g) Flash point no data available

h) Evaporation rate no data available

i) Flammability (solid, gas) no data available

j) Upper/lower

flammability or

explosive limits

no data available

k) Vapour pressure no data available

l) Vapour density no data available

m) Relative density no data available

n) Water solubility no data available

o) Partition coefficient: noctanol/

water

no data available

p) Autoignition

temperature

no data available

q) Decomposition

temperature

no data available

r) Viscosity no data available

s) Explosive properties no data available

t) Oxidizing properties no data available

Other safety information

no data available

 

10. STABILITY AND REACTIVITY

Reactivity

no data available

Chemical stability

no data available

Possibility of hazardous reactions

no data available

Conditions to avoid

no data available

Incompatible materials

Strong oxidizing agents

Hazardous decomposition products

Other decomposition products - no data available

Sigma - T4446 Page 5 of 6

 

11. TOXICOLOGICAL INFORMATION

Information on toxicological effects

Acute toxicity no data available

Skin corrosion/irritation

Serious eye damage/eye irritation  Eyes - rabbit - Severe eye irritation Remarks: Severe eye irritation

Respiratory or skin sensitization no data available

Germ cell mutagenicity no data available

Carcinogenicity IARC: No component of this product present at levels greater than or equal to 0.1% is identified as

probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity no data available

Specific target organ toxicity - single exposure no data available

Specific target organ toxicity - repeated exposure no data available

Aspiration hazard no data available

Potential health effects Inhalation May be harmful if inhaled. May cause respiratory tract irritation.

Ingestion May be harmful if swallowed.

Skin May be harmful if absorbed through skin. May cause skin irritation.

Eyes Causes eye burns.

Additional Information RTECS: Not available

 

12. ECOLOGICAL IN FORMATION

Toxicity no data available

Persistence and degradability no data available

Bioaccumulative potential no data available

Mobility in soil no data available

Results of PBT and vPvB assessment no data available

Other adverse effects no data available

 

13. DISPOSAL CONSIDERATIONS

Waste treatment methods

Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional

waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent

and burn in a chemical incinerator equipped with an afterburner and scrubber.

Contaminated packaging Dispose of as unused product.

 

14. TRANSPORT INFORMATION

UN-Number

ADR/RID: - IMDG: - IATA: -

UN proper shipping name

ADR/RID: Not dangerous goods

IMDG: Not dangerous goods

IATA: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA: -

Packaging group

ADR/RID: - IMDG: - IATA: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for users

no data available

 

15. REGULATORY INFORMATION

This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.

Safety, health and environmental regulations/legislation specific for the substance or mixture

no data available

Chemical Safety Assessment no data available

16. Other Information

Nile Chemicals. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. NILE CHEMICALS. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, NILE CHEMICALS. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.

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