NILE CHEMICALS

DIETHYLENE TRIAMINE PENTA ACETIC ACID (DTPA)

 


1. Product Identification

Synonyms: (Diethylenetrinitrilo) pentaacetic acid; DTPA; [[(Carboxymethyl)imino]bis(ethylene nitrilo)] tetraacetic acid,
CAS No.: 67-43-6
Molecular Weight: 393.35
Chemical Formula: [ (HOOCCH2)2NCH2CH2]2 NCH2COOH


2. Composition/Information on Ingredients

 

  Ingredient                                CAS No         Percent        Hazardous                                 
  ---------------------------------------   ------------   ------------   ---------  
  Diethylenetriamine Pentaacetic Acid       67-43-6          90 - 100%       Yes                                                                   
  Nitrilotriacetic Acid                     139-13-9          < 0.2%         Yes                                                                 
 

3. Hazards Identification

-----------------------------------------------------------------------------------------------------------
Health Rating: 1 - Slight (Cancer)
Flammability Rating: 1 - Slight
Reactivity Rating: 0 - None
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES; LAB COAT; PROPER GLOVES
Storage Color Code: Green (General Storage)
-----------------------------------------------------------------------------------------------------------
Potential Health Effects
----------------------------------
Information on the human health effects from exposure to this substance is limited.
Inhalation: Causes irritation to the respiratory tract. Symptoms may include coughing, shortness of breath.
Ingestion: Large oral doses may cause irritation to the gastrointestinal tract.
Skin Contact: Causes irritation to skin. Symptoms include redness, itching, and pain.
Eye Contact: Causes irritation, redness, and pain.
Chronic Exposure: Repeated exposure to nitrilotriacetic acid may cause kidney damage and alter genetic material.
Aggravation of Pre-existing Conditions: No information found.


4. First Aid Measures

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact:Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact:Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures

Fire:As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion:Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media:Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information:In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.


6. Accidental Release Measures

Remove all sources of ignition. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Clean up spills in a manner that does not disperse dust into the air. Use non-sparking tools and equipment. Reduce airborne dust and prevent scattering by moistening with water. Pick up spill for recovery or disposal and place in a closed container. US Regulations (CERCLA) require reporting spills and releases to soil, water and air in excess of reportable quantities.


7. Handling and Storage

Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Wear special protective equipment (Sec. 8) for maintenance break-in or where exposures may exceed established exposure levels. Wash hands, face, forearms and neck when exiting restricted areas. Shower, dispose of outer clothing, change to clean garments at the end of the day. Avoid cross-contamination of street clothes. Wash hands before eating and do not eat, drink, or smoke in workplace. Isolate from incompatible substances. Avoid dust formation and control ignition sources. Employ grounding, venting and explosion relief provisions in accord with accepted engineering practices in any process capable of generating dust and/or static electricity. Empty only into inert or non-flammable atmosphere. Emptying contents into a non-inert atmosphere where flammable vapors may be present could cause a flash fire or explosion due to electrostatic discharge. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.


8. Exposure Controls/Personal Protection

Airborne Exposure Limits:None established.
Ventilation System:A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved):For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerine, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection:Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection:Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.


9. Physical and Chemical Properties

Appearance: White crystals.
Odor: No information found.
Solubility: Slightly soluble in water.
Density: No information found.
pH: No information found.
% Volatiles by volume @ 21C (70F): 0
Boiling Point: Not applicable.
Melting Point: 220 - 222C (428 - 432F)
Vapor Density (Air=1): No information found.
Vapor Pressure (mm Hg): No information found.
Evaporation Rate (BuAc=1): No information found.


10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers.
Conditions to Avoid: Dusting and incompatibles.


11. Toxicological Information


Diethylenetriaminepentaacetic acid: Oral mouse LD50: 4840 mg/kg; Nitrilotriacetic acid; Oral rat LD50: 1100 mg/kg, Investigated as a tumorigen and a mutagen.
  --------\Cancer Lists\------------------------------------------------------
                                         ---NTP Carcinogen---
  Ingredient                             Known    Anticipated    IARC Category
  ------------------------------------   -----    -----------    -------------
  Diethylenetriamine Pentaacetic Acid     No          No            None
  (67-43-6)
  Nitrilotriacetic Acid (139-13-9)        No          Yes            2B

12. Ecological Information

Environmental Fate:No information found.
Environmental Toxicity:No information found.


13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.


14. Transport Information

Not regulated.


15. Regulatory Information

  --------\Chemical Inventory Status - Part 1\---------------------------------
  Ingredient                                       TSCA  EC   Japan  Australia
  -----------------------------------------------  ----  ---  -----  ---------
  Diethylenetriamine Pentaacetic Acid (67-43-6)     Yes  Yes   Yes      Yes                                     
  Nitrilotriacetic Acid (139-13-9)                  Yes  Yes   Yes      Yes                                     
 
  --------\Chemical Inventory Status - Part 2\---------------------------------
                                                          --Canada--
  Ingredient                                       Korea  DSL   NDSL  Phil.
  -----------------------------------------------  -----  ---   ----  -----
  Diethylenetriamine Pentaacetic Acid (67-43-6)     Yes   Yes   No     Yes                         
  Nitrilotriacetic Acid (139-13-9)                  Yes   Yes   No     Yes            
 
  --------\Federal, State & International Regulations - Part 1\----------------
                                             -SARA 302-    ------SARA 313------
  Ingredient                                 RQ    TPQ     List  Chemical Catg.
  -----------------------------------------  ---   -----   ----  --------------
  Diethylenetriamine Pentaacetic Acid        No    No      No         No
  (67-43-6)
  Nitrilotriacetic Acid (139-13-9)           No    No      Yes        No
 
  --------\Federal, State & International Regulations - Part 2\----------------
                                                        -RCRA-    -TSCA-
  Ingredient                                 CERCLA     261.33     8(d)
  -----------------------------------------  ------     ------    ------
  Diethylenetriamine Pentaacetic Acid        No         No         No              
  (67-43-6)
  Nitrilotriacetic Acid (139-13-9)           No         No         No          
Chemical Weapons Convention:  No     TSCA 12(b):  No     CDTA:  No
SARA 311/312:  Acute: Yes      Chronic: Yes  Fire: No  Pressure: No
Reactivity: No          (Mixture / Solid)

WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO THE STATE OF CALIFORNIA TO CAUSE CANCER.
Australian Hazchem Code: None allocated.
Poison Schedule: None allocated.
WHMIS:  
This MSDS has been prepared according to the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all of the information required by the CPR.

16. Other Information

Disclaimer: Nile Chemicals. provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose. NILE CHEMICALS. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS. ACCORDINGLY, NILE CHEMICALS. WILL NOT BE RESPONSIBLE FOR DAMAGES RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.

 

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